Editorial Commentary: Failure of Adjunctive Valacyclovir to Improve Outcomes in Herpes Simplex Encephalitis

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Editorial Commentary: Failure of Adjunctive Valacyclovir to Improve Outcomes in Herpes Simplex Encephalitis.

The majority of cases of acute encephalitis remain of unknown etiology despite extensive diagnostic evaluations [1, 2]. Herpes simplex virus (HSV) is the most common identified cause of acute sporadic encephalitis in the Western world, accounting for approximately 20% of total cases of identified cause [3]. Classic studies by the National Institute of Allergy and Infectious Diseases Collaborati...

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Failure of Adjunctive Valacyclovir to Improve Outcomes in Herpes Simplex Encephalitis

The majority of cases of acute encephalitis remain of unknown etiology despite extensive diagnostic evaluations [1, 2]. Herpes simplex virus (HSV) is the most common identified cause of acute sporadic encephalitis in the Western world, accounting for approximately 20% of total cases of identified cause [3]. Classic studies by the National Institute of Allergy and Infectious Diseases Collaborati...

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Fluent Aphasia From Herpes Simplex Encephalitis

The present case report introduces a patient with fluent aphasia, anterograde amnesia and anosmia due to herpes simplex encephalitis after her first delivery. The left medial temporal lobe was one of the main areas involved. On aphasia testing she showed severe anomia on both confrontation and free recall, agraphia, alexia, repetition disorder and some auditory comprehension impairments. Therap...

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Herpes simplex encephalitis

We presented four cases diagnosed with Herpes simplex virus encephalitis of those treated in our clinic in 2006 one of whom died, one recovered without any sequels. Two cases were left with advanced motor mental sequel. In this paper, clinical and laboratory findings along with diagnosis and treatment of Herpes simplex virus encephalitis were discussed.

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Herpes simplex encephalitis.

A 28-year-old woman presented with a one day history of high fever and partial seizures with secondary generalization. This was preceded by a three week history of headache, ataxia, and fatigue. An initial computed tomogram head scan showed a low density mass lesion in the right frontal operculum without enhancement. On the next day, a repeat scan showed a new frontopolar, expansile, low densit...

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ژورنال

عنوان ژورنال: Clinical Infectious Diseases

سال: 2015

ISSN: 1058-4838,1537-6591

DOI: 10.1093/cid/civ373